Perfusion on
Your Terms
Your Research Pushes Boundaries
–
Your Perfusion System Should Too
Medicine and Engineering in True Collaboration
Our Vision: Collaborative Approach
At IDSC, ETH Zurich, we advance the forefront of engineering research. We believe that we can save lives when medicine and engineering work together — not in parallel, but in true collaboration.
Whether you're exploring novel surgical approaches, testing new drug interactions, or refining complex perfusion protocols, you need access to the most advanced perfusion machine that science has to offer — without being burdened by technical limitations. This is why we don’t just provide you a perfusion machine — we work alongside you. From initial concept to conducting experiments, we adapt our platform to your needs, tailoring every aspect to fit your research. Our modular architecture and advanced control systems ensure technical precision, while our collaborative approach ensures you’re never alone in the process.
perfusionX Technology
Hardware
Modular, adaptable, and built to integrate seamlessly with your workflow.
This perfusion setup is tailored to the needs of your experimental or surgical protocol.
Software
Developed at ETH Zurich, our control algorithms and AI modules push
perfusion precision to a new level, supporting even the most sensitive protocols.
User Interface
No technical distractions. Our user interface is designed by UX experts and enables fully automated one-click protocols so you can stay focused on what matters: Developing next-gen medical procedures.
Existing Collaborations — From Idea to Application
Understanding the behavior of novel carriers for radioactive markers is a complex challenge in nuclear medicine. Through ex-vivo liver perfusion, we support physicists in studying the distribution and dynamics of these markers within liver tissue by providing a controlled, high-fidelity environment for precise and repeatable investigations.
Pharmakokinetics
In polytrauma cases, severely injured extremities are often discarded as stabilizing the patient takes priority. We collaborate with leading experts in ex-vivo perfusion, supporting the development of a novel limb perfusion protocol in an animal model. This protocol significantly extends preservation time beyond conventional cold storage, representing a crucial step toward enabling delayed replantation of limbs after major trauma.
Life and Limb
Preclinical studies in porcine models are resource-intensive and costly. In collaboration with perfusion experts at the University Hospital Zurich, we’ve reduced perfusion-related costs by a factor of ten. This was made possible by shifting to a small-animal perfusion model—enabled by our advanced control algorithms and adaptable system architecture.
Cost-Effective Perfusions
About Us
David Machacek, PhD
With a doctoral focus on modular control systems, David developed algorithms designed to simplify complex technical systems — empowering users to focus fully on their domain expertise. This philosophy is embedded in our one-click solutions, enabling seamless perfusion control with surgical precision.
Rafael Fröhlich, MSc
An expert in intelligent control and AI, Rafael brings advanced algorithmic thinking to life within our platform. From ultra-low-flow stability to adaptive system responses, his work ensures that the machine intelligently supports even the most sensitive and demanding perfusion protocols.
We are two engineers from ETH Zurich, united by a shared mission: to bring intelligent, user-centric perfusion technology into the hands of clinicians and researchers. Together, we combine deep engineering expertise with a clinical mindset — designing tools that don’t just perform, but enable progress in transplantation and experimental medicine. We collaborate with practitioners and medical research teams within Switzerland and the EU, and our research group is headed by Professor Christopher Onder, ETH Zurich.